Keywords
biología molecular
contexto histórico determinante
historia de la biología
filosofía de la biología Human Genome Project
Molecular biology
Determining historical context
History of biology
Philosophy of biology
How to Cite
Abstract
The scientific dimension of the Human Genome Project (HGP) refers to a set of entities of a biological order: nitrogenous bases, genes, enzymes, SNP's1, etc., on which the technological operations that give rise to the sequencing of the genome are exercised. . A closer examination shows that all the bodies, morphologies and structures that are a constituent part of the HMP can be circumscribed to the field of molecular biology, with which they are logically given on the same scale. This first assumption, which will have to be verified in the subsequent reconstruction, allows us to return to the course of the constitution of molecular biology, as a factor in the determining historical context of the HMP, without having to go back to previous processes in the history of biology to give reason for the conformation and connection of the strokes that are part of the reference figure.
References
Bueno, Gustavo (1991-1993), Teoría del cierre categorial, vols. I-V. Oviedo, Pentalfa.
Crick, Francis (1989), Qué loco propósito. Una visión personal del descubrimiento científico. Barcelona, Tusquets.
Crick, Francis (1958), «On protein synthesis», in Symposia of the Society for Experimental Biology, n.º 12, pp. 138-163.
Hidalgo, Alberto (1982), «La Biología molecular: ¿revolución o cierre?», en Alberto Hidalgo y Gustavo Bueno Sánchez (eds.), Actas del I Congreso de Teoría y Metodología de las Ciencias. Oviedo, Pentalfa, Oviedo.
Kay, Lil E. (2000), «A Book of Life? How a Genetic Code Became a Languaje», en Philip R Sloan (ed.), Controlling Our Destinies. Historical, Ethical Philosophical and Theological Perspectives on the Human Genome Project. Indiana, University of Notre Dame Press, págs.103-106.
Klug, Aaron (2008), «El descubrimiento de la doble hélice del ADN», en Torsten Krude (ed.), Cambios en la ciencia y en la sociedad. Madrid, Akal.
Lee, Thomas F. (2000), El Proyecto Genoma Humano, Rompiendo el código genético de la vida. Barcelona, Gedisa.
McCarthy, Maclyn (1986), The Transforming Principle. Discovering that Genes Are Made of DNA. New York, W. W. Norton & Company.
Melero, José A. (2003), «ADN↔ARN→proteína (El dogma central de la biología molecular)», en Pedro García Barreno (dir.), Cincuenta años de ADN. La doble hélice. Madrid, Espasa, págs. 123-147.
Olby, Robert (1991), El camino hacia la doble hélice. Madrid, Alianza.
Schrödinger, Erwin (1983), ¿Qué es la vida? Barcelona, Tusquets.
Watson, James (2003), ADN. El secreto de la vida. Madrid, Taurus.
Watson, James (2000), La doble hélice. Madrid, Alianza.
Watson, James y Crick, Francis [1953], «Genetical Implications of the Structure of Deoxyribonucleic Acid», en Pedro García Barreno (dir.), Cincuenta años de ADN. La doble hélice. Madrid, Espasa, 2003, págs. 118-120.
Watson, James y Crick, Francis [1953], «Molecular Structure of Nucleic Acids. A Structure for Deoxyribose Nucleic Acid», en Pedro García Barreno (dir.), Cincuenta años de ADN. La doble hélice. Madrid, Espasa, 2003, págs. 114-115.
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